• Publications internationales

EL-KIRAT-CHATEL S., BEAUSSART A., MATHELIE-GUINLET M., DUFRENE Y.-F., 2020. The importance of force in microbial cell adhesion. Current Opinion In Colloid & Interface Science 47, 111-117     Réf. HAL: hal-02396634.  [doi]

VOURIOT E., BIHANNIC I., BEAUSSART A., WALDVOGEL Y., RAZAFITIANAMAHARAVO A., RIBEIRO T., FARINHA J.-P.-S., BELOIN C., DUVAL J.-F.-L., 2020. Electrophoresis as a simple method to detect deleterious actions of engineered nanoparticles on living cells. Environmental Chemistry 17, 39-53     .  [doi]

BEAUSSART A., EL-KIRAT-CHATEL S., 2019. Microbial adhesion and ultrastructure from the single-molecule to the single-cell levels by Atomic Force Microscopy. The Cell Surface 5, 100031     Réf. HAL: hal-02353034.  [doi]

LAVIALE M., BEAUSSART A., ALLEN J., QUILES F., EL-KIRAT-CHATEL S., 2019. Probing the Adhesion of the Common Freshwater Diatom Nitzschia palea at Nanoscale. Acs Applied Materials & Interfaces 11, 48574-48582     .  [doi]

PAGNOUT C., SOHM B., RAZAFITIANAMAHARAVO A., CAILLET C., OFFROY M., LEDUC M., GENDRE H., JOMINI S., BEAUSSART A., BAUDA P., DUVAL J.-F.-L., 2019. Pleiotropic effects of rfa-gene mutations on Escherichia coli envelope properties. Scientific Reports 9 (1)     Réf. HAL: hal-02185099.  [doi]

VALSECCHI I., LAI J.I., STEPHEN-VICTOR E., PILLÉ A., BEAUSSART A., LO V., PHAM C.L.L, AIMANIANDA V., KWAN A.-H., DUCHATEAU M., GIANETTO Q.-G., MATONDO M., DUFRÊNE Y.-F., BAYRY J., GUIJARRO J.-I., SUNDE M., LATGÉ J.-P., 2019. Assembly and disassembly of Aspergillus fumigatus conidial rodlets. The Cell Surface 5, 100023     .  [doi]

AIMANIANDA V., WONG S.-S.-W., VENUGOPALAN L.-P., KARNAM A., BEAUSSART A., BAYRY J., JAYAPAL J.-M., KUPPAMUTHU D., LATGE J.-P., PRAJNA L., 2018. Two Aspergillus species, A. flavus and A. fumigatus - a comparative study of their conidial surface properties and immunological reactivities Medical Mycology 56, S2-S2.  [doi]

BEAUSSART A., BELOIN C., GHIGO J.-M., CHAPOT-CHARTIER M.-P., KULAKAUSKAS S., DUVAL J.-F.-L., 2018. Probing the influence of cell surface polysaccharides on nanodendrimer binding to Gram-negative and Gram-positive bacteria using single-nanoparticle force spectroscopy Nanoscale 10, 12743-12753.  [doi]

BEAUSSART A., CAILLET C., BIHANNIC I., ZIMMERMANN R., DUVAL J.-F.-L., 2018. Remarkable reversal of electrostatic interaction forces on zwitterionic soft nanointerfaces in a monovalent aqueous electrolyte: an AFM study at the single nanoparticle level Nanoscale 10, 3181-3091.  [doi]

EL-KIRAT-CHATEL S., BEAUSSART A., 2018. Probing Bacterial Adhesion at the Single-Molecule and Single-Cell Levels by AFM-Based Force Spectroscopy. Nanoscale Imaging: Methods And Protocols 1 814, 403-414.  [doi]

GUERIN J., BURGAIN J., FRANCIUS G., EL-KIRAT-CHATEL S., BEAUSSART A., SCHER J., GAIANI C., 2018. Adhesion of Lactobacillus rhamnosus GG surface biomolecules to milk proteins Food Hydrocolloids 82, 296-303.  [doi]

NGO T.-C., KALINOVA R., MINCHEVA R., BEAUSSART A., HENNEBERT E., FLAMMANG P., DUFRENE Y., DUBOIS P., LAZZARONI R., LECLERE P., 2017. On the Bioadhesive Properties of Silicone-Based Coatings by Incorporation of Block Copolymers Bio-Inspired Structured Adhesives: Biological Prototypes, Fabrication, Tribological Properties, Contact Mechanics, And Novel Concepts 9, 303-343.  [doi]

BEAUSSART A., ABELLAN-FLOS M., EL-KIRAT-CHATEL S., VINCENT S.-P., DUFRENE Y.-F., 2016. Force Nanoscopy as a Versatile Platform for Quantifying the Activity of Antiadhesion Compounds Targeting Bacterial Pathogens Nano Letters 16 (2), 1299-1307.  [doi]

RAMEAU R.-D., JACKSON D.-N., BEAUSSART A., DUFRENE Y.-F., LIPKE P.-N., 2016. The Human Disease-Associated A beta Amyloid Core Sequence Forms Functional Amyloids in a Fungal Adhesin Mbio 7 (1), e01815-15.  [doi]

SCHULTE T., MIKAELSSON C., BEAUSSART A., KIKHNEY A., DESHMUKH M., WOLNIAK S., PATHAK A., EBEL C., LOFLING J., FOGOLARI F., HENRIQUES-NORMARK B., DUFRENE Y.-F., SVERGUN D., NYGREN P.-A., ACHOUR A., 2016. The BR domain of PsrP interacts with extracellular DNA to promote bacterial aggregation; structural insights into pneumococcal biofilm formation Scientific Reports 6, 32371.  [doi]

• A. Beaussart, M. Abellc
  n-Flos, S. El-Kirat-Chatel, S.P. Vincent, Y.F. Dufrêne, Force nanoscopy as a versatile platform for quantifying the activity of antiadhesion compounds targeting bacterial pathogens, Nano Lett., 2016, 16, 129;1307.

• A. Le Cigne, L. Chièze, A. Beaussart, S. El-Kirat-Chatel, Y.F. Dufrêne, S. Dedieu, C. Schneider, L. Martiny, J. Devy, M. Molinari, Analysis of the effect of LRP-1 silencing on the invasive potential of cancer cells by nanomechanical probing and adhesion force measurements using atomic force microscopy, Nanoscale, 2016, 8, 7144-7154.

• C. Formosa-Dague, C. Feuillie, A. Beaussart, S. Derclaye, S. Kucharíkovc
  , I. Lasa, P. Van Dijck, Y.F. Dufrêne, Sticky matrix: adhesion mechanism of the staphylococcal polysaccharide intercellular adhesin, ACSNano, 2016, 10, 34433452.

• R.D. Rameau, D.N. Jackson, A. Beaussart, Y.F. Dufrêne, P.N. Lipke, The human disease-associated Abeta amyloid core sequence forms functional amyloids in a fungal adhesin, mBio, 2016, 7 2016, e01815-15.

• T. Schulte, C. Mikaelsson, A. Beaussart, A. Kikhney, M. Deshmukh, S. Wolniak, A. Pathak, C. Ebel, J. Löfling, B. Henriques-Normark, Y. F. Dufrêne, D. Svergun, P. Nygren, A. Achour, The BR domain of PsrP interacts with extracellular DNA to promote bacterial aggregation - structural insights into pneumococcal biofilm formation, Scientific report, 2016, 6, 32371.

•  A. Beaussart, S. El-Kirat-Chatel, T. Fontaine, J. P. Latge, Y. F. Dufrêne, Nanoscale biophysical properties of the cell surface galactosaminogalactan from the fungal pathogen Aspergillus fumigatus, Nanoscale, 2015, 7:36, 14996-15004. 

• A. Beaussart, T. Brandhorst, Y.F. Dufrêne, B.S. Klein, Blastomyces Virulence Adhesin-1 Protein Binding to Glycosaminoglycans Is Enhanced by Protein Disulfide Isomerase, mBio, 2015, 6:5, e01403-15.

• *S. El-Kirat-Chatel, *A. Beaussart, S. Derclaye, D. Alsteens, S. Kucharikova, P. Van Dijck, Y.F. Dufrêne, Force nanoscopy of hydrophobic interactions in the fungal pathogen Candida glabrata, ACS Nano, 2015, 9:2, 1648-1655. *contributed equally.

•  K. Heim, R.M.A. Sullan, P. Crowley, S. El-Kirat-Chatel, A. Beaussart, W. Tang, R. Besingi, Y.F. Dufrêne, J. Bready, Identification of a Supramolecular Functional Architecture of Streptococcus mutans Adhesin P1 on the Bacterial Cell Surface, Journal of Biological Chemistry, 2015, 290:14, 9002-9019.

• S. El-Kirat-Chatel, A. Beaussart, S.P. Vincent, M. Abellan Flos, P. Hols, P.N. Lipke, Y.F. Dufrêne, Forces in yeast flocculation, Nanoscale, 2015, 7:5, 1760-1767.

• S. Ardisson, C. Fumeaux, M. Bergé, A. Beaussart, L. Théraulaz, S.K. Kadhakrishnan, Y.F. Dufrêne, P.H. Viollier, Cell cycle constraints on capsulation and genetic exchange, eLife, 2014, 3 e03587.

•  D. A. Beattie, J. Addai-Mensah, A. Beaussart, G. V. Franks, K. Y. Yeap, In situ particle film ATR FTIR spectroscopy of poly (N-isopropyl acrylamide) (PNIPAM) adsorption onto talc, Physical Chemistry Chemical Physics, 2014, 16(45), 25143-25151.

•  A. Beaussart, C. Péchoux, P. Trieu, M.Y. Mistou, Y. Dufrêne, Molecular mapping of the cell wall polysaccharides of the human pathogen Streptococcus agalactiae, Nanoscale, 2014, 6:24, 14820-14827.

•  A. Beaussart, A.E. Baker, S.L. Kuchma, S. El-Kirat-Chatel, G.A. oToole, Y.F. Dufrêne, Nanoscale adhesion forces of Pseudomonas aeruginosa type IV pili, ACS Nano, 2014, 8:10, 10723-10733.

•  P. Herman, S. El-Kirat-Chatel, A. Beaussart, T. Foster, Y.F.  Dufrêne, The binding force of the staphylococcal adhesin SdrG is remarkably strong, Molecular Microbiology, 2014, 93:2,356-368.

• J. Bayry, A. Beaussart, Y.F. Dufrêne , M. Sharma, K. Bansal, O. Kniemeyer,  V. Aimanianda, A. A. Brakhage, S. V. Kaveri, K. J. Kwon-Chung, J-P Latgé, A. Beauvais, Surface structure characterization of Aspergillus fumigatus conidia mutated in the melanin synthesis pathway and their human cellular immune response, Infection and Immunity, 2014, 82:8, 3141-3152 (highlighted in the journal Spotlight report). 

•  A. Beaussart, S. El-Kirat-Chatel, R. M. A. Sullan, D. Alsteens, P. Herman, S. Derclaye, Y.F. Dufrêne, Quantifying the forces guiding microbial cell adhesion using single-cell force spectroscopy, Nature Protocols, 2014, 9:5, 1049-1055 (featured protocol). 

• *A. Beaussart and S. El-Kirat-Chatel, Atomic force microscopy and spectroscopy: a versatile toolbox to decipher Candida albicans pathogenicity, Journal of Bionanoscience, 2014, 8:6.*corresponding author

• *R. M. A. Sullan, *A. Beaussart, P. Tripathi, S. Derclaye, S. El-Kirat-Chatel, J.K. Li, Y.J. Schneider, J. Vanderleyden, S. Lebeer, Y.F. Dufrêne, Single-cell force spectroscopy of pili-mediated adhesion, Nanoscale, 2014, 6:2, 1134-1143 *contributed equally.

•  S. El-Kirat-Chatel, A. Beaussart, C. D. Boyd, G. A. O'Toole, Y.F. Dufrêne, Single-cell and single-molecule analysis deciphers the localization, adhesion and mechanics of the biofilm adhesin LapA, ACS Chemical Biology, 2014, 9:2, 485-494.

• A. Beaussart, T.C. Ngo, S. Derclaye, R. Kalinova, R. Mincheva, P. Dubois, R. Lazzaroni, P. Leclère , Y.F. Dufrêne, Chemical force microscopy of stimuli-responsive adhesive copolymers, Nanoscale, 2014, 6:1, 565-571.

• P. Herman, S. El-Kirat-Chatel, A. Beaussart, J. Geoghegan, T. Vanzieleghem, T. Foster, P. Hols,  J. Mahillon, Y.F.  Dufrêne, Forces driving the attachment of Staphyloccocus epidermidis to fibrinogen-coated surfaces, Langmuir, 2013, 29:42, 13018-13022.

• A. Beaussart, P. Herman, S. El-Kirat-Chatel, P.N. Lipke, S. Kucharikova, P. Van Dijck, Y.F. Dufrêne, Single-cell force spectroscopy of the medically-important Staphyloccocus epidermidis-Candida  albicans interaction, Nanoscale, 2013, 5:22,10894-10900. (Journal cover).

•  S. El-Kirat-Chatel, D. Mil-Homens, A. Beaussart, A.M Fialho, Y.F. Dufrêne, Single-molecule atomic force microscopy unravels the binding mechanism of a Burkholderia cenocepacia trimeric autotransporter adhesin. Molecular Microbiology, 2013, 89:4, 649-659.

•  D. Alsteens, A. Beaussart, S. Derclaye, S. El-Kirat-Chatel, H.R. Park, P.N. Lipke, Y.F. Dufrêne, Single-cell force spectroscopy of Als mediated fungal adhesion, Analytical methods, 2013, 20:3, 3657-3662 (Journal cover). 

• A. Beaussart, T. Rolain, M. C. Duchêne, G. Andre, P. Hols, Y.F. Dufrêne, Binding mechanism of the bacterial autolysin Acm2: low affinity, broad specificity and multifunctionality, Biophysical Journal, 2013, 105:3, 620-629.

• T. Rolain, E. Bernard, A. Beaussart, H. Degand, P. Courtin, W. Egge-Jacobsen, P. A. Bron, P. Morsomme, M. Kleerebezem, M-P Chapot-Chartier, Y. F. Dufrêne, P. Hols, O-glycosylation as a novel control mechanism of peptidoglycan hydrolase activity, Journal of Biological Chemistry, 2013, 288, 22233-22247.

•  D. Alsteens, A. Beaussart, S. El-Kirat-Chatel, R. Sullan, Y.F. Dufrêne, Atomic force microscopy: a new look at pathogens, PloS Pathogens, 2013, 9:9.

•  S. El-Kirat-Chatel, A. Beaussart, D. Alsteens, A. Sarazin, T. Jouault, Y.F. Dufrêne, Single-molecule analysis of the major glycopolymers of pathogenic and non-pathogenic yeast cells, Nanoscale, 2013, 5:11, 4855-4863.

•  A. Beaussart, S. El-Kirat-Chatel, P. Herman, D. Alsteens, J. Mahillon, P. Hols, Y.F. Dufrêne, Single-cell force spectroscopy of probiotic bacteria, Biophysical Journal, 2013, 104:9, 1886-1892 (featured article).

•  *P. Tripathi, *A. Beaussart, D. Alsteens, V. Dupres, I. Claes, I von Ossowski, A. Palva, S. Lebeer, J. Vanderleyden, Y.F. Dufrêne, Adhesion and nanomechanics of pili from probiotic Lactobacillus rhamnosus GG, ACS Nano, 2013, 7 :4, 3685-3697. *contributed equally

•  S. El-Kirat-Chatel, A. Beaussart, D. Alsteens, D.N Jackson, P.N. Lipke PN, Y.F. Dufrêne, Nanoscale analysis of caspofungin-induced cell surface remodelling in Candida albicans, Nanoscale, 2012, 5 :3, 1105-1115.

• A. Beaussart, D. Alsteens, S. El-Kirat-Chatel, P.N. Lipke, S. Kucharikova, P. Van Dijck, Y.F. Dufrêne, Single-molecule imaging and functional analysis of Als adhesins and mannans during Candida albicans morphogenesis, ACS Nano, 2012, 6 :12, 10950-10964.

•  P. Tripathi, A. Beaussart, G. Andre, T. Rolain, S. Lebeer, J. Vanderleyden, P. Hols, Y.F. Dufrêne, Towards a nanoscale view of lactic acid bacteria, Micron, 2012, 43 :12, 1323-1330.

•  J.J. Heinisch, P.N. Lipke, A. Beaussart, S. El-Kirat-Chatel, V. Dupres, D. Alsteens, Y.F. Dufrêne, Atomic force microscopy - Looking at mechanosensors on the cell surface, Journal of Cell Science, 2012, 125 :18, 4189-4195.

•  A. Beaussart, L. Petrone, A. Mierczynska-Vasilev, A.J. McQuillan, D.A. Beattie, In situ ATR FTIR study of dextrin adsorption on anatase TiO₂, Langmuir, 2012, 28 :9, 4233-4240.

• A. Beaussart, L. Parkinson, A. Mierczynska-Vasilev, D.A. Beattie, Adsorption of modified dextrins on molybdenite: AFM imaging, contact angle, and flotation studies, Journal of Colloid and Interface Science, 2012, 368 :1, 608-615. 

•  P. Tripathi, V. Dupres, A. Beaussart, S. Lebeer, I.J.J Claes, J. Vanderleyden, Y.F. Dufrêne, Deciphering the nanometer-scale organization and assembly of Lactobacillus rhamnosus GG pili using atomic force microscopy, Langmuir, 2012, 28:4, 2211-2216.

•  D.A. Beattie, A. Beaussart, A. Mierczynska-Vasilev, S.L. Harmer, B. Thierry, L. Puskar, M. Tobin, Synchrotron FTIR microscopy of Langmuir-Blodgett monolayers and polyelectrolyte multilayers at the solid-solid interface, Langmuir, 2012, 28 :3, pp. 1683-1688. 

• A. Beaussart, A. Mierczynska-Vasilev, S.L. Harmer, D.A. Beattie, The role of mineral surface chemistry in modified dextrin adsorption, Journal of Colloid and Interface Science, 2011, 357 :2, 510-520.

•  A. Beaussart, A. Mierczynska-Vasilev, D. A. Beattie, Evolution of carboxymethyl cellulose layer morphology on hydrophobic mineral surfaces:  variation of polymer concentration and ionic strength, Journal of Colloid and Interface Science, 2010, 346, 303-310.

•  A. Beaussart, L. Parkinson, A. Mierczynska-Vasilev, J. Ralston, D. A. Beattie, Effect of adsorbed polymers on bubble particle attachment, Langmuir, 2009, 25 :23, 13290-13294.

• A. Beaussart, A. Mierczynska-Vasilev, D. A. Beattie, Adsorption of dextrin on hydrophobic minerals, Langmuir, 2009, 25 :17, 9913-992.

• J. Li, A. Beaussart, Y. Chen, A.F.T. Mak, Transfer of apatite coating from porogens to scaffolds: uniform apatite coating within porous (DL-lactic-co-glycolic acid) scaffold in vitro, Journal of biomedical materials research, Part A, 2007, 80 :1, 226-33.

Chapitres de livres

• S. El-Kirat-Chatel and *A. Beaussart, Probing bacterial adhesion at the single-molecule and single-cell levels by AFM-based force spectroscopy, Methods en Molecular Biology, In press.* corresponding author

•  T.C. Ngo, R. Kalinova, R. Mincheva, A. Beaussart, E. Hennebert, P. Flammang, Y.F. Dufrêne, P. Dubois, R. Lazzaroni, P. Leclère, On the structural, mechanical and adhesive properties of silicone-based coatings made by incorporation of block copolymers, Springer, In press.

• S. El-Kirat-Chatel and *A. Beaussart, AFM tools to characterize the physico-chemical and mechanical properties of pathogens. In: NATO Science for Peace and Security Series, Springer, 2014, p1-15 .* corresponding author

• E. Dague, A. Beaussart, D. Alsteens, Nanomechanics of yeast surfaces revealed by AFM. In: B. Bushan (Editor), Scanning probe microscopy in nanoscience and nanotechnology, Springer-Verlag, Berlin Heidelberg, 2013, 7, 171-193.